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Clinical Trials/NCT04737525
NCT04737525
Active, not recruiting
Not Applicable

The Influence of a Connective Tissue Graft Versus a Porcine-derived Membrane (Mucoderm) on the Aesthetic Outcome After Immediate Placement and Loading of a Tapered Dental Implant in the Anterior Maxilla. A Randomized Controlled Clinical Trial.

Vilniaus Implantologijos Centro (VIC) Klinika1 site in 1 country50 target enrollmentAugust 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Immediate Implants
Sponsor
Vilniaus Implantologijos Centro (VIC) Klinika
Enrollment
50
Locations
1
Primary Endpoint
Aesthetic evaluation
Status
Active, not recruiting
Last Updated
5 years ago

Overview

Brief Summary

Esthetic outcome of immediate implant placement in fresh extraction sockets remains one of the biggest challenges in implant dentistry. Recently a method to preserve the peri-implant tissues was introduced using provisional restoration, allogenic bone and soft tissue thickening. However, the evidence that this immediate provisialisation with soft tissue grafting using different grafting materials results in constantly high Pink Esthetic scores, especially compared to the delayed loading approach is still lacking.

The aim of this clinical trial is to assess the esthetic outcome of immediate temporization of immediately placed and loaded tapered implants in fresh extraction sockets with bone and soft tissue augmentation, using either a connective tissue graft (CTG) or a porcine-derived membrane (Mucoderm) in maxillary anterior sites.

The secondary objectives are to investigate the influence of immediate loading on the success rate of tapered implants and crestal bone levels.

Registry
clinicaltrials.gov
Start Date
August 1, 2017
End Date
February 10, 2031
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Vilniaus Implantologijos Centro (VIC) Klinika
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Males and females of at least 18 years of age
  • 1 implant per patient
  • Subject must have voluntarily signed the informed consent before any study related action, are willing and able to attend scheduled follow-up visits, and agree that the pseudonymized data will be collected and analyzed
  • Anterior single teeth (canines and incisors) in both jaws
  • Class I extraction socket (intact buccal wall) or Class II (1/3 of buccal wall)
  • No recession of gingival contour of tooth to be extracted
  • No periodontal bone loss of neighboring anterior teeth
  • No implants in neighboring teeth
  • Atraumatic extraction of the tooth with intact socket walls remaining

Exclusion Criteria

  • Deep bite (severe II class)
  • Heavy smokers (more than 10 cigarettes/day)
  • Systemic disease (diabetes, osteoporosis)
  • Primary stability after implant placement not achieved

Outcomes

Primary Outcomes

Aesthetic evaluation

Time Frame: Change from baseline, 1 year, 5 and 10 years after prosthetic delivery

Pink esthetic score (PES) according to Fürhauser et al. 2005 Seven variables will be evaluated: mesial papilla, distal papilla, soft-tissue level, soft-tissue contour, alveolar process deficiency, soft-tissue color and texture. Using a 0-1-2 scoring system, 0 being the lowest, 2 being the highest value, the maximum achievable PES is 14. For the PES assessment, frontal photographs will be taken using a digital camera with a flash strobe mounted on a tripod (Canon 350d, 3456×2304 pixel resolution). PES will be assessed at baseline (Final Prosthesis), 3- and 12-month visit.

Secondary Outcomes

  • Recession of gingiva (REC)(Change from baseline, 1 year, 5 and 10 years after prosthetic delivery)

Study Sites (1)

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