The Efficacy of Continuous Intercostal Nerve Blocks in the Treatment of Patients With Multiple Rib Fractures
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Length of hospital stay
研究概览
简要总结
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of continuous intercostal nerve block (CINB) in the treatment of patients admitted to the adult trauma service with rib fractures. The effectiveness of CINB as adjunctive treatment will be compared to standard medical therapy involving nonsteroidal and intravenous/oral opioid medications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects will be at least 18 years old
- •Subjects will have 2 or more identified rib fractures
- •Subjects will be willing to provide informed consent for procedure
- •Subjects will be identified as appropriate for initiation of continuous nerve block therapy for treatment of rib fracture associated pain.
排除标准
- •Documented allergy to study medication
- •Epidural catheter use
- •Prisoners
- •Refusal of CINB therapy
研究组 & 干预措施
continuous intercostal nerve block (CINB)
patients admitted to the adult trauma service with rib fractures who are receiving CINB
干预措施: Ropivacaine (Drug)
continuous intercostal nerve block (CINB)
patients admitted to the adult trauma service with rib fractures who are receiving CINB
干预措施: Non steroidal anti-inflammatory drug and opioids (Drug)
standard medical care
patients admitted to the adult trauma service with rib fractures who are receiving standard medical care
干预措施: Non steroidal anti-inflammatory drug and opioids (Drug)
结局指标
主要结局
Length of hospital stay
时间窗: 7 days
time from randomization until the time of discharge
次要结局
- Patient reported quality of life(7 days)
- Patient daily pain scores(7 days)
- Modified Morphine Equivalent (MME) differences(7 days)
- spirometry values(7 days)
- hospital-free days(30 days)
- mean respiratory rates(7 days)
研究者
Zachary Warriner
Assistant Professor
University of Kentucky