Efficacy of Eplerenone monotherapy and Valsartan monotherapy on patients of Subclinical Cushing's syndrome with hypertension and non-functioning adrenocortical adenoma with hypertension.
Not Applicable
- Conditions
- Subclinical Cushing's syndrome with hypertension and non-functioning adrenocortical adenoma with hypertension.
- Registration Number
- JPRN-UMIN000002925
- Lead Sponsor
- Hiroshima University Hospital Department of Endocrinology and Diabetes mellitus
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
(a) Patients with a history of severe cardiovascular or cerebrovascular disease or renal failure. (b) Patients with aldosterone producing adenoma, Cushing's syndrome and malignant tumor. (c) Patients who have taken ARB, ACEI, aldosterone antagonist or diuretics therapy. (d) Patients have contraindication of Eplerenone and Valsartan. (e) Patients with severe liver damage. (f) Patients are pregnant or patients breast-feeding, potentially pregnant. (g) Patients who are diagnosed to be ineligible by the investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method