Curcumin Supplementation and Type 2 Diabetes
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Triglyceride
研究概览
简要总结
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects. Recently, the use of natural plant products has gained more attention among scientists in order to prevent diabetic vascular complications. Curcumin is a natural yellow product derived from the turmeric rhizome which has shown to be non-toxic and exhibits various bio¬logical activities such as anti-oxidant, anti-inflammatory, anti-carcinogenic, and anti-diabetic effects. Curcumin is effective in reducing glycemic index and hyperlipidemia in rodent models and is relatively inexpensive and safe. Most of the studies conducted on animal model, and just a few of them are on human model. The present study was planned to evaluate the effects of curcumin supplementation on serum levels of lipid profile and inflammatory markers in patients with type 2 diabetes
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Tendency to participate
- •Age range of 40-65
- •Suffering from diabetes type 2 ( between 1 to 10 yeares)
- •BMI 18/5-30
- •Patients with diabetes who administer oral hypoglycemic agents and do not use
排除标准
- •patients with liver diseases
- •patients with kidney diseases
- •patients with inflammatory diseases
- •patients with liver diseases
- •Administering herbal agents
- •Administering multivitamins and minerals in past 3 months
研究组 & 干预措施
intervention
500 mg curcumin capsule
干预措施: curcumin (Dietary Supplement)
placebo
500 mg placebo
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Triglyceride
时间窗: 12 weeks
次要结局
- C-Reactive Protein(12 weeks)
研究者
Dr Azita Hekmatdoost
Principal Investigator
National Nutrition and Food Technology Institute