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Clinical Trials/NCT05295381
NCT05295381
Completed
Not Applicable

Effect of Abdominal Weight Training Assisted by Cough Assist Machine on Lung Function in the Patients With Prolonged Mechanical Ventilation

Liu Shih Feng1 site in 1 country40 target enrollmentAugust 21, 2019
ConditionsPMV

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
PMV
Sponsor
Liu Shih Feng
Enrollment
40
Locations
1
Primary Endpoint
Maximum inspiratory pressure change by the intervention
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The patients with prolonged mechanical ventilation (PMV) have the risk of ineffective coughing and infection due to diaphragm weakness, making it more difficult to wean. This study aimed to explore the intervention of abdominal weight training (AWT) with/ without cough machine (CM) on lung function, respiratory muscle strength and cough ability in these patients.

Detailed Description

Methods 40 patients with PMV were randomly assigned to three groups: AWT group (n=12), AWT+CM group (n=14) and control group (n=14). The effectiveness on pulmonary function, respiratory muscle strength and cough ability were compared among these three groups.

Registry
clinicaltrials.gov
Start Date
August 21, 2019
End Date
August 13, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Liu Shih Feng
Responsible Party
Sponsor Investigator
Principal Investigator

Liu Shih Feng

Chief of department of respiratory therapy in Kaohsiung CGMH

Chang Gung Memorial Hospital

Eligibility Criteria

Inclusion Criteria

  • (1) Invasive ventilator users,
  • (2) Hemodynamically stable,
  • (3) Intubated endotracheal tube or tracheotomy tube,
  • (4) Clearly conscious and cooperative,
  • (5) Vital capacity (VC) \<10ml/kg

Exclusion Criteria

  • (1) Unconscious or unwilling to sign the informed consent form,
  • (2) No spontaneous breathing,
  • (3) Active bleeding with unstable hemodynamics,
  • (4) Acute infection symptoms,
  • (5) Abdominal distension, digestion problems (including nausea and vomiting),
  • (6) Severe heart failure (ejection fraction ≤ 30%),
  • (7) Unhealed wounds in the chest and abdomen,
  • (8) Bullous emphysema,
  • (9) Sensitive pneumothorax or mediastinal pneumothorax,
  • (10) Recent history of traumatic stress,

Outcomes

Primary Outcomes

Maximum inspiratory pressure change by the intervention

Time Frame: Change between 1 day before and 2 weeks after the intervention

lung function

Maximum expiratory pressure change by the intervention

Time Frame: Change between 1 day before and 2 weeks after the intervention

lung function

Secondary Outcomes

  • vital capacity change by the intervention(Change between 1 day before and 2 weeks after the intervention)

Study Sites (1)

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