Comparison of the efficacy and tolerability of adapalene gel 0.1% versus tretinoin gel 0.05% in patients with mild to moderate acne vulgaris
Phase 2
Completed
- Conditions
- Acne vulgaris.Acne vulgaris
- Registration Number
- IRCT201403109014N31
- Lead Sponsor
- Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Any patient with mild to moderate acne vulgaris without limitation of age and gender.
Exclusion criteria: (a) Pregnancy or breast feeding; (b) using medication that have interaction with the drug under study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of the improvement of acne lesions. Timepoint: at zero time and then at 4th and 12th weeks after treatment. Method of measurement: based on the Global Acne Grading System with comparison of the photos taken from the location of the lesions.
- Secondary Outcome Measures
Name Time Method ocal dry skin. Timepoint: at 4th and 12th weeks after treatment. Method of measurement: through physical examination.;Local erythema. Timepoint: at 4th and 12th weeks after treatment. Method of measurement: through clinical examination.;Local skin irritation. Timepoint: at 4th and 12th weeks after treatment. Method of measurement: through taking history of the patient.