Physiological Response to 5 Days Fasting

Not Applicable

Completed

• Conditions: Healthy

• Registration Number: NCT04452916
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-6-23
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

Inclusion Criteria:<br><br> - Men and women<br><br> - 20-50 years<br><br> - Body mass index 20-30 kg/m2<br><br>Exclusion Criteria:<br><br> - Clinically relevant heart, lung, liver, and kidney diseases<br><br> - Any prescribed medication (except for oral contraceptives)<br><br> - Current or chronic infection<br><br> - Intake of antibiotics within 6 months before study entry<br><br> - Fasting week within 6 months before study entry<br><br> - Habitual use of dietary supplements<br><br> - Food intolerances<br><br> - Pregnancy, lactation<br><br> - Vegan diet<br><br> - Smokers<br><br> - In addition for fMRI: sensorineural hearing loss, tinnitus, metal implants, electric<br> devices

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Resting Energy Expenditure

Secondary Outcome Measures

Name	Time	Method
Resting Energy Expenditure - Recovery;Resting Respiratory Exchange Ratio;Office systolic blood pressure;Office diastolic blood pressure;Fecal microbiome composition;Fecal and serum metabolome;Change in immune cell phenotypes;Glucose variability;Neural correlates of emotion processing;Neural correlates of food-specific delay discounting;Perceived Stress Questionaire (PSQ);Perceived Self Efficiency;PANAS Positive Affect Subscale (GESIS Panel);PANAS Negative Affect Subscale (GESIS Panel);International Physical Activity Questionaire (IPAQ, long version)