Pilot Study on the impact of timing of antimicrobial prophylaxis for elective Caesarean section at term on infant gut microbiome

Not Applicable

• Conditions: O82; Single delivery by caesarean section

• Registration Number: DRKS00025305
• Lead Sponsor: niversitätsklinikum Schleswig-Holstein

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-04-26
• Study Start: 2021-05-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

elective Caesarean section at term, no PROM, not in labor, no antibiotics for three months, no smoking, no diabetes, singleton pregnancy

Exclusion Criteria

preterm birth, labor, PROM, smoking, diabetes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
microbiome signature of infants in the first days of life as determined by 16S rRNA gene sequencing and analysis of antibiotic resistance genes

Secondary Outcome Measures

Name	Time	Method
microbiome composition at one month and one year of life and maternal risk for surgical site infections