Effect of Short term Versus Long term Antimicrobial Prophylaxis in preventing postoperative Infectious Complications among patients undergoing Transurethral Resection of Prostate at KCMC
- Conditions
- Urological and Genital Diseases
- Registration Number
- PACTR201808161376054
- Lead Sponsor
- THRIVE 2 master grant
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 88
Catheterized patients 18 years or older with Bladder Outlet Obstruction secondary to an enlargement of the prostate with bladder outlet obstruction, admitted for Transurethral Resection of Prostate.
• Patients with a urine culture and sensitivity testing showing no resistance to gentamicin and/or ciprofloxacin.
• Who speak and understand Kiswahili
• Who provide a written informed consent
• Patients who will fail to void postoperative after removal of catheter (the number will be recorded)
Patients with renal failure (serum creatinine above 200µmol/l) , uncontrolled DM and Immunocompromised
• Patients with internal prosthesis.
• Patients who received antibiotics within one week prior to surgery.
• Patients who do not wish to participate.
• Patients whose urine culture are resistant to gentamicin and/or ciprofloxacin( on long term arm ).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of asymptomatic bacteriuria as determined by mid stream urinalysis and urine culture and sensitivity
- Secondary Outcome Measures
Name Time Method incidence of symptomatic urinary tract infections , fever and clinical sepsis.