Treatment of ekkushtha(psoriasis)by virechana karma and shiravedhan

Phase 2

Recruiting

Conditions: Patients suffereing from psoriasis

Registration Number: CTRI/2016/06/007035

Lead Sponsor: AYUSH department

Brief Summary: Inthis clinical trial total 64 patients were registered and randomly divided intotwo groups. In group A *Virechana karma* follÂ· Inthis clinical trial total 64 patients were registered and randomly divided intotwo groups. In group A *Virechana karma* followedby *shaman yogas* and in group B *Virechana*followed by *Siravedhana Karma* and after that shaman yogas was given.Among them 28 patients were completed the treatment in group A and 30 patientswere completed the treatment in group B. 4 patients left before completion oftreatment in group A and 2 patients in group B. After completion of treatment patientsGroupAshowshighly significant(p<0.001) decrease in *Mandala* (Erythema) by 59.14%, *Matsyashakalopama*(Scaling) by 51.78%, *Rukshata* (Dryness) by 54.25%, *Aswedana* (Anhydrosis)by 58.1%, *Daha* (Burning sensation) by 56.67%, *Bahalatva* (Thickeningof skin lesion) by 47.36%, *Kandu* (Itching) by 56.00%, *Srava*(discharge) by 54.56%, DermatologyLife Quality Index (DLQI) by 56.57% and Psoriasis Area Severity Index (PASI)score by 52.28% and in group B alsoshows highly significant (p<0.001) decrease the *Mandala* (Erythema)by 65.9%, *Matsyashakalopama* (Scaling) by 63.67%, *Rukshata* (Dryness)by 60.24%, *Aswedana* (Anhydrosis) by 55.56%, *Daha* (Burningsensation) by 65.35%, *Bahalatva* (Thickening of skin lesion) by 56.84%, *Kandu*(Itching) by 65.51%, *Srava*( discharge) by 76.92% Dermatology Life Quality Index(DLQI) by 62.24% and Psoriasis Area Severity Index (PASI) score by 55.19%.

In Overall Effect of Therapy Marked improvement was found in 3(10.00%) patients ingroup B and 1(3.57%) patients in Group A. Moderate improvement was found in 20(66.66%) patients in Group B and 17 (60.71%) patient in Group A.

Inthe present study When Chi squareâ€“ test was applied for comparison betweentwo groups there was not any significant difference found between two groups Howeverpercent wise group B showed better results.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients with all forms of Ekakushtha (Psoriasis) who are clinically fit to undergo Virechana and Shiravedhana.

Exclusion Criteria

Patients who are clinically unfit for Virechana and Shiravedhana Age 16yrs & 60yrs.
Pregnant women Uncontrolled Diabetes Mellitus & Hypertension Any other serious systemic illness Chronicity more than 10 years Patients who are not willing to be included in the study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in signs and symptoms of psoriasis	after 2 month of completion of treatment

Secondary Outcome Measures

Name	Time	Method
Efficacy and Safety	after completion of 2 month of treatment

Trial Locations

Locations (1): hospital of IPGT AND RA panchkarama department opd no 22
🇮🇳
Jamnagar, GUJARAT, India
hospital of IPGT AND RA panchkarama department opd no 22
🇮🇳Jamnagar, GUJARAT, India
Drjayesh odedra
Principal investigator
9429563141
drjayeshodedra@gmail.com