The Effects of an Intradialytic Progressive Resistance and Aerobic Training in End-stage Renal Disease Patients Undergoing Hemodialysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 主要终点
- Body composition by Dual-energy x-ray absorptiometry (DEXA)
研究概览
简要总结
We aimed to investigate the effect of a progressive resistance training and aerobic training protocol on functional capacity, body composition and quality of life.
详细描述
Subjects were randomized into group A and B: group A (n=30) exercised for the first 6 months while group B (n=31) performed a placebo exercise initially (3 months) and cross-over to aerobic exercised for 3 months more.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •older than 18 years
- •more than three months of hemodialysis vintage
- •under the permission of their nephrologist
- •agreement to be randomly assigned and undergo study protocols
排除标准
- •Patients in wheelchair, presenting disability, or those who had amputation and malformation of the lower limbs, causing impaired walking
- •presenting representative blindness
结局指标
主要结局
Body composition by Dual-energy x-ray absorptiometry (DEXA)
时间窗: before and after 12 and 24 weeks of study
Dual-energy x-ray absorptiometry (DEXA) was used to measure lean body mass (LBM), fat mass (FM) and Bone Mineral Contend (BMC) in grams using a total body scan, following the equipment description - HOLOGIC Discovery Wi (Hologic inc, Waltham, MA, USA). Body composition variables included in this study were total mass, body FM, LBM and legs LBM, and BMC. Body composition was assessed after a hemodialysis day; time after previous hemodialysis did not exceed eight hours.
次要结局
- Quality of life assessed by the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36)(before and after 12 and 24 weeks of study)
- Functional capacity(before and after 12 and 24 weeks of study)
- Pulmonary capacity(before and after 12 and 24 weeks of study. Additionally this variable was assessed over the three time points before and after one hemodialysis session.)
研究者
Clara S C Rosa
PhD Student
Universidade Estadual Paulista Júlio de Mesquita Filho