Comparing methods to manage recurrent fluid build up around the lung caused by problems with the heart - what is the best way to measure this and which method do patients prefer?
- Conditions
- Recurrent pleural effusion secondary to heart failureRespiratory
- Registration Number
- ISRCTN10499680
- Lead Sponsor
- orth Bristol NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 18
1. The presence of a recurrent pleural effusion secondary to heart failure that has not responded to medical therapy
2. Sufficient pleural fluid for IPC insertion
3. Symptomatic breathlessness warranting pleural intervention
4. Pleural infection excluded to satisfaction of treating physician
5. Expected survival >12 weeks
6. Written informed consent to trial participation
1. Age <18 years
2. Known pleural malignancy
3. Pregnancy, lactation or intention to become pregnant
4. Absolute contraindication to IPC insertion or therapeutic aspiration of pleural fluid
5. Previous attempts at ipsilateral pleurodesis
6. Evidence of extensive lung entrapment on chest x-ray or CT, or significant fluid loculation on ultrasound scan, to a level which would normally be a contraindication to attempted talc pleurodesis or IPC insertion.
7. Inability to give informed consent
8. Patient has no access to a telephone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of participants recruited from those who meet the eligibility criteria: the study will be deemed successful if the absolute number recruited is at least 32, and =50% eligible patients are successfully randomised; Timepoint(s): Randomisation
- Secondary Outcome Measures
Name Time Method