Pilot testing of a new approach to improving the prescribing of many drugs for older people who live in their own home and are cared for by general practitioners

Not Applicable

Completed

• Conditions: Multiple medications (polypharmacy) in older adults; Not Applicable

• Registration Number: ISRCTN41009897
• Lead Sponsor: Queen's University Belfast

Brief Summary

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/34261527/ Process evaluation (added 16/07/2021) 2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33741071/ (added 05/08/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36088445/ (added 12/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-11-19
• Study Completion: 2022-01-31
• Last Update Posted: 26 September 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

GP practices:
1. Provide written informed consent and Research Governance sign-off
2. Stable internet service in order to access the video

Patients:
1. =70 years of age
2. Receiving four or more regular medicines
3. Resident in the community
4. In receipt of a valid general medical services (GMS) card in the Republic of Ireland, or in the case of Northern Ireland patients, registered for NHS primary care services
5. Registered with and/or regularly attending the practice for a minimum of 12 months

Exclusion Criteria

GP practices:
1. Participating in other studies related to medicines management in older people

Patients:
1. Care home residents
2. Cognitively impaired
3. Terminal illness
4. Involved in other Investigational Medicinal Product (IMP) or medicines management studies

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Current primary outcome measure as of 09/12/2020:<br><br> 1. Recruitment: The number of patients and GP practices contacted and recruited. The retention rate of patients and GP practices at the end of the study<br> 2. Health outcomes: Medication appropriateness assessed using STOPP/START criteria at baseline, six months’ and nine months’ post-initial medication review in the intervention arm and the equivalent time points in the control arm<br><br> _____<br><br> Previous primary outcome measure:<br><br> 1. Recruitment: The number of patients and GP practices contacted and recruited. The retention rate of patients and GP practices at the end of the study<br> 2. Health outcomes: Medication appropriateness assessed using STOPP/START criteria at baseline, six months’ and 12 months’ post-baseline<br>