Choice of Valve Substitute in the Era of Oral Anticoagulation Self-Management

Completed

• Conditions: Anticoagulation; Mechanical Heart Valve Replacement

• Registration Number: NCT01269905
• Lead Sponsor: Johann Wolfgang Goethe University Hospital

Brief Summary

The optimal valve substitute for patients between 60-70 years is controversial. We compared anticoagulation-related adverse events (ARAE) in patients receiving mechanical heart valve replacement (MHVR) on INR self-management vs. stentless bioprosthesis, to assess whether the risk of structural valve deterioration (SVD) is still out-weighted by the benefit of not requiring permanent anticoagulation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2005-01
• Study First Submitted: 2011-01-03
• Study First Submitted QC: 2011-01-03
• Last Update Submitted: 2011-01-03
• Study First Posted: 2011-01-04
• Last Update Posted: 2011-01-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• heart valve replacement

Exclusion Criteria

• CABG
• Afib

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified