Prevention of asthma and respiratory symptoms in young children with a nutritional interventio

Recruiting

• Conditions: Asthma; bronchusobstruction; 10024967

• Registration Number: NL-OMON52918
• Lead Sponsor: Ziekenhuisgroep Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Inclusion criteria are;
- Children between 1 and 4 years old
- Paediatric Asthma Score is 7 or above 7, with these scores there is a high
chance of developing asthma (chance>25%).

Exclusion Criteria

-not understanding the Dutch language by the parents
-a cow's milk protein allergy (or any other allergy to one of the components of
the food intervention) at the time of the intervention. If patients never
consumed cow*s milk proteins before, the risk of an allergy is unclear. In that
case they cannot be included. If they have proven to tolerate cow*s milk
protein in whatever form, they can be included.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints: a decrease in TRACK scores and LRSQ scores of<br /><br>the dietary intervention group compared to the control group.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome measures are medication use, microbiome, immune analysis<br /><br>(cytokine profile, selective antibody production), IgA in saliva, adherence to<br /><br>the diet as well as growth parameters such as height, weight and Body Mass<br /><br>Index (BMI).</p><br>