Screening for pneumonia: A comparison of Ultra Low Dose chest CT and conventional chest radiography

Completed

• Conditions: Pneumonia; pulmonary infection; 10024970

• Registration Number: NL-OMON45887
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-11-02
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 95

Inclusion Criteria

Patients that are having symptoms of a pneumonia and were referred by their general practitioner for additional imaging with chest CRX

Exclusion Criteria

- Pregnancy
- Younger than 18 years
- Unable to give informed consent
- In case subject does not want to be informed about additional findings

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Our primary objective is to establish device diagnostic clinical performance of<br /><br>ULD-CT in order to proof it is more accurate to detect pneumonia when comparing<br /><br>to standard CXR.<br /><br><br /><br>We will ask 3 different radiologist to evaluate both examinations on whether or<br /><br>not the subject has air space consolidation, and if yes, where it is located.<br /><br>Location of the consolidation can either be in right upper lobe (RUL), middle<br /><br>lobe (ML), right lower lobe(RLL), left upper lobe (LUL) or left lower lobe<br /><br>(LLL). There is no cut off for the extend of consolidation that is seen in<br /><br>subjects lung. Each radiologist evaluates both examinations of the subject<br /><br>(paired group). Data outcome will be stored in MACRO. Results regarding our<br /><br>primary objective will be binary outcome results (yes or no consolidation). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Our secondary objective is to describe additional findings that were seen on<br /><br>both modalities. Each radiologist has to describe if there are additional<br /><br>pathologic findings visible on both CXR as well as ULD-CT examinations.<br /><br>Options are:<br /><br>1. no additional finding; 2. solid leasion; 3. pleural effusion; 4. nodules; 5.<br /><br>Atelectasis; 6.other</p><br>