statin in PVR related redetachment

Phase 3

Recruiting

• Conditions: secondary retinal detachment.; Retinal detachment with retinal break; H33.0

• Registration Number: IRCT20191207045645N1
• Lead Sponsor: Vice Chancellor for Research, Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

age>40
primary attachment following PPV with silicon oil or sf6 tamponade vs scleral buckle
regular follow up
all of the surgery was done with a single experienced surgeon in a single center

Exclusion Criteria

combined RD
recurrent RD
RRD associated with giant tear
Secondary RD due to other than PVR
intraoperative complications like vitreous or suprachoroidal hemorrhages
Other concomitant eye diseases affecting the retina including glaucoma, CSR, acquired and congenital retinal dystrophies, etc.
PVRc
lactation and pregnancy
systemic steroid use
Taking different medications that can interfere with statin use

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Secondary retinal detachment. Timepoint: 1 day, 1 week and 1,3 and 6 months after the surgery. Method of measurement: examinations and OCT imaging.

Secondary Outcome Measures

Name	Time	Method
Comparing the rate of retinal detachment in groups of using statin and using placebo. Timepoint: day 1, week 1, month 1,3 and 6. Method of measurement: slit lamp examination and OCT.