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临床试验/NCT07596264
NCT07596264已完成不适用

Development and Validation of an Interpretable Machine Learning Model for Predicting Venous Thromboembolism(VTE)in Intensive Care Unit (ICU) Patients

Beijing Tsinghua Chang Gung Hospital1 个研究点 分布在 1 个国家目标入组 12,061 人开始时间: 2022年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
12,061
试验地点
1
主要终点
validate an interpretable machine learning (ML) model to predict VTE in ICU patients

研究概览

简要总结

Venous thromboembolism remains a leading cause of preventable mortality in intensive care unit (ICU) patients. Existing risk-stratification tools were developed in general medical populations and lack ICU-specific predictors. This study was to develop and validate an interpretable machine learning (ML) model to predict VTE in ICU patients.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age ≥18 years;
  • ICU length of stay ≥48 hour
  • the first ICU admission

排除标准

  • VTE diagnosed prior to ICU admission
  • VTE diagnosed within 24 hours of ICU admission
  • >20% missing values in key variables

结局指标

主要结局

validate an interpretable machine learning (ML) model to predict VTE in ICU patients

时间窗: the first day after the patients leaf ICU

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Weiwei Wu

vice president

Beijing Tsinghua Chang Gung Hospital

研究点 (1)

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