Three different modalities of treatment for osteoarthritis knee in eastern Indian population.

Completed

• Conditions: patient with primary osteoarthritis of knee

• Registration Number: CTRI/2017/08/009480

Brief Summary

The objective of the study is to compare the results of conservative therapy, intra articular steroid injection therapy and intra articular hyaluronic acid injection therapy in primary osteoarthritis of knee. Our study is a prospective study which includes a total of 45 patients receiving the above treatment. All the patients were followed for upto 6 months. We did not loss any patients in the follow up.

In summary, the results from our study suggests that corticosteroids are more effective than hyaluronic acid in the short term (2 months), whereas hyaluronic acid is more effective in the long term (2nd  month upto  4th  month). In case of patients undergoing conservative therapy there is no much significance improvement.  Awareness of this pattern of response is useful to the clinician in formulating a therapeutic plan for patients with knee OA.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-02
• Study Completion: 2014-03-31
• Last Update Posted: 2017-08-18

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Patient above 40 years with primary osteoarthritis of knee including both male and female.

Exclusion Criteria

• Age below 40 years.
• 1.Pain in knee after trauma.
• 2.Local infections in and around knee joint.
• 3.Uncontrolled diabetes mellitus.
• 4.Severe joint deformity.
• 5.Patient on anticoagulant therapy and allergies to avian products.
• 6.Patient with history of surgery in and around the knee.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The results from our study suggests that Corticosteroids are more effective than Hyaluronic acid in the short term (2 months), whereas Hyaluronic acid is more effective in the long term (2nd month upto 4th month). In case of patients undergoing conservative therapy there is no much significance improvement.	Follow up is done at 2 months,4 months and 6 months.

Trial Locations

Locations (1)

kolkata medical college; 🇮🇳 Kolkata, WEST BENGAL, India

kolkata medical college

🇮🇳Kolkata, WEST BENGAL, India

Dr Wanlamkupar Khongwir

Principal investigator

8013055428

khongwirwanlam@gmail.com