Multiple micronutrient supplementation improves growth and hemoglobin of infants in Gaza Strip, Palestine

Not Applicable

Completed

• Conditions: utritional status including growth parameters, biomedical measures, and dietary intakes; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN57594793
• Lead Sponsor: niversity Putra Malaysia

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/33278899/ (added 07/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-01-30
• Study Start: 2018-03-20
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Male or female infants
2. Aged 5 months + 2 weeks
3. Have normal z scores (>-2 to <+2 SD) of Wt/age, Lt/age and Hc/age
4. Have birth weight = 2.5 to = 4 kg
5. Have appropriate for gestational age (between the 10th and 90th percentile)
6. Have blood level of hemoglobin = 11 gram per deciliter
7. Breastfed for at least 4 months
8. Visited the UNRWA clinics for vaccination and/or routine child's growth follow up

Exclusion Criteria

1. Preterm infants (?37 weeks)
2. Infants who have a history of chronic diseases (e.g. failure to thrive and metabolic or endocrine disorders)
3. Infants of diabetic mothers
4. Have a history of complications during delivery (aspiration, trauma)
5. Have a history of congenital and/or acquired neurological diagnosis (e.g., Down syndrome or cerebral palsy)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Anthropometric measures, including body weight, length, circumferences of the head, waist, and mid-upper arm, and triceps and subscapular skinfold thickness, measured at baseline and throughout the study period (every 3 to 6 months). Z scores of these measures calculated by the WHO Anthro software, version 3.2.2, waist circumference z scores calculated based on the reference data obtained from Turkish under-six years children<br> 2. Hemoglobin concentration: finger or heel prick blood obtained by the lab technician of the UNRWA clinic and analyzed for hemoglobin level using spectrophotometer (colorimeter) at baseline, end of the intervention, and 3 months after the end of intervention period<br>

Secondary Outcome Measures

Name	Time	Method
Calorie and nutrient intakes, including energy, carbohydrate, fat, protein, iron, vitamin A, and vitamin D, assessed using one day of 24-hour diet recall at baseline, 6 months of intervention, and at the end of the intervention period