Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Not Applicable

Completed

• Conditions: Postoperative Complications
• Interventions: Other: local surface anesthesia; Device: Laryngeal tube

• Registration Number: NCT02961075
• Lead Sponsor: The Second Affiliated Hospital of Dalian Medical University

Brief Summary

Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Detailed Description

Fiberoptic bronchoscopy (FOB) is the essential procedures for diagnosis and treatment of respiratory diseases。 Fever following FOB has been frequently reported. Fever is usually caused by patient discomfort and delay recovery from illness, or even worse. The reported frequency of this complication ranges from 1 to 20%. According to previous reports, postbronchoscopy fever is associated with advanced age, the presence of abnormal bronchoscopic findings,documented endobronchial obstruction, bronchoscopic intervention for malignancy, BAL, bronchial brushing, endotoxin contamination during bronchoscopy, instillation of topical anesthetic through the bronchoscope, abnormal differential cell counts in the BAL fluid (BALF), bacterial growth in the BALF culture,and the severity of bleeding. At present, guidelines recommend sedation and analgesia combined with airway surface anesthesia for Fiberoptic bronchoscopy. laryngeal spray and cricothyroid anesthesia often used in clinical.Cricothyroid local anesthesia has a good effect, but it is an invasive operation, this is risk factors for fever after bronchoscopy.Therefore, to compare fever in the two kinds of airway anesthesia on Bronchoscopy . So as to provide the local anesthesia method with little influence on the patient.

Study Timeline

• Study Start: 2016-05
• Status Verified: 2016-11
• Primary Completion: 2016-11
• Study Completion: 2016-11
• Study First Submitted: 2016-11-09
• Study First Submitted QC: 2016-11-09
• Study First Posted: 2016-11-10
• Last Update Submitted: 2017-01-23
• Last Update Posted: 2017-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• ASA I-III

Exclusion Criteria

• use of immunosuppressive agents or corticosteroids
• body temperature 37.3°C during the 24 h prior to FOB,intubation or mechanical ventilation
• therapeutic bronchoscopy (foreign body removal, bronchial toilet, or stenting), discharge within 24 h of FOB
• surgical or diagnostic procedures within 24 h of FOB.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Laryngeal tube	Laryngeal tube	local surface anesthesia by Laryngeal tube
Cricothyroid	local surface anesthesia	local surface anesthesia by Cricothyroid
Laryngeal tube	local surface anesthesia	local surface anesthesia by Laryngeal tube

Primary Outcome Measures

Name	Time	Method
Fever	48 hour	Fever was defined as an axillary body temperature 37.3°C

Trial Locations

Locations (1)

The Second Hospital of Dalian Medical University; 🇨🇳 Dalian, Liaoning, China