NL-OMON39422
Recruiting
N/A
Brain Structure and Development in Children and Adolescents with Prader-Willi Syndrome: A Combined Structural and Functional MRI Study - Brain Structure and Development in Children with Prader-Willi Syndrome
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Prader-Willi Syndrome
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 160
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Children and adolescents with genetically confirmed PWS and known genetic defect between 6\-25 years old and healthy age\- and sex\-matched controls
- •Written Informed consent of the caregivers and children and adolescents older than 12 years and assent of patients/children younger than 12 years
- •Written informed consent of healthy adult controls
- •Successful completion of the mock MRI scanner protocol for healthy controls under 12 years old
Exclusion Criteria
- •Other chromosomal abnormalities
- •Claustrophobia
- •Contra\-indications for MRI scanner
- •The use of medication for treating anxiety, mood disorders or psychiatric disturbances including the regular use of homeopathic St John\*s wort preparations for longer than two weeks
- •Expected or proven non\-compliance
Outcomes
Primary Outcomes
Not specified
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