Sensorimotor adaptation and learning in the control of human standing balance in cerebellar ataxia patients
- Conditions
- sensorimotor learning for standing balance in cerebellar patientsbalance instability and motor control problems
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 260
For healthy controls:
• In overall good health
• Age: 18 - 90 years old
For patients:
• Adults between the age of 18 - 90 years old who have been diagnosed with a
cerebellar lesion.
• Patients will be invited to participate in the study within 3-12 months after
their initial diagnosis.
For healthy controls:
• History of neurological or psychiatric disorders
• Taking acute or chronic psychoactive drugs
• Alcoholism
• History of balance problems
• Pregnant women or women currently breastfeeding
• A prior neuromuscular injury (regardless of source)
• Incompetence to give informed consent
For patients:
• Unable to walk 10 metres unaided
• Unable to stand freely for 10 seconds with the eyes closed
• Diagnosed with polyneuropathy
• Taking acute or chronic psychoactive drugs
• Alcoholism
• Pregnant women or women currently breastfeeding
• Incompetence to give informed consent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameters are measures of standing balance behaviour (whole<br /><br>body kinematics and kinetics) and evoked balance responses (probed with sensory<br /><br>and/or mechanical stimuli). </p><br>
- Secondary Outcome Measures
Name Time Method <p>Healthy controls and cerebellar patient participants will be asked to visit the<br /><br>Department of Neuroscience at Erasmus at least one time for the selected<br /><br>experiment. During the visit, they will perform tasks specific to each<br /><br>experiment. The robotic balance simulator does not present significant<br /><br>discomfort or risk for the participants. </p><br>