The Role of Surgical Resection AND Stereotactic Radiosurgery in Primary Central Nervous System -Diffuse Large B Cell Lymphoma

Completed

• Conditions: Primary Central Nervous System Diffusing Large Cell Lymphoma

• Registration Number: NCT07007611
• Lead Sponsor: jiahong Deng

Brief Summary

The objective of this observational study is to understand the long-term impact of surgery and gamma knife treatment on primary central diffuse large B-cell lymphoma. The main questions it aims to answer are:

Can surgery and gamma knife prolong the survival period of patients with primary central diffuse large B-cell lymphoma? Participants who have already incorporated surgery and gamma knife as part of the routine medical care for patients with primary central diffuse large B-cell lymphoma will answer questions about survival period within 5 years.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-12-01
• Primary Completion: 2023-12-01
• Status Verified: 2025-05
• Study Completion: 2025-05-01
• Study First Submitted: 2025-05-28
• Study First Submitted QC: 2025-05-28
• Study First Posted: 2025-06-06
• Last Update Submitted: 2025-06-07
• Last Update Posted: 2025-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

pathologically confirmed PCNS-DLBCL complete clinical records detailing treatment methods and surgical approaches.

Exclusion Criteria

incomplete systemic treatment data loss to follow-up after initial contact prior receipt of whole-brain radiotherapy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival	December 2006 and December 2023	The time from diagnosis to death of the patient