Epidural in Paediatric Cardiac Surgery
Phase 2
Completed
- Conditions
- Health Condition 1: Q20-Q28- Congenital malformations of the circulatory system
- Registration Number
- CTRI/2020/09/027549
- Lead Sponsor
- DGAFMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 136
Inclusion Criteria
Paediatric patients ( <14 yrs) undergoing on pump cardiac surgery
Exclusion Criteria
Off pump cardiac surgery
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum levels of cytokine IL6Timepoint: Baseline, postoperative at 4, 24 and 48 hours
- Secondary Outcome Measures
Name Time Method 1. Inflammatory marker (IL6,8,10, TNFalpha, CRP) <br/ ><br>2. Metabolic marker (glucose) <br/ ><br>3. Endocrine marker (Cortisol) <br/ ><br>4. Cardiac marker (Trop I, CKMB) <br/ ><br>5. Renal marker (NGAL, renal NIRS) <br/ ><br>6. HAemodynamic (HR, IBP) <br/ ><br>7. ICU complications (LOS, MV duration, mortality)Timepoint: postoperative (4 hrs, 24 hrs and 48 hrs)