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临床试验/KCT0000809
KCT0000809已完成未知

A comparison study of ondansetron and palonosetron for the prevention of postoperative nausea and vomiting in women patients using intravenous patient-controlled analgesia

Soon Chun Hyang University Hospital Seoul0 个研究点目标入组 204 人开始时间: 待定最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
204

研究概览

简要总结

. The incidences of nausea (55.6%), vomiting (14.1%) in the palonosetron group were not different significantly when compared with that of nausea (58.3%), vomiting (19.8%) in the ondansetron group during 24 hours after surgery (P > 0.05). There were no significant differences between the two groups in the severity of nausea, the use of rescue antiemetics, adverse effects, and satisfaction with IV-PCA (P > 0.05).

研究设计

研究类型
Interventional Study

入排标准

年龄范围
20(Year) 至 70(Year)(—)
性别
Female

入选标准

  • 1) Heathy women patients who scheduled elective operation umder general anesthesia
  • 2) 20-70years old patients who scheduled to receiv an intravenous patient-controlled analgesia using fentanyl

排除标准

  • Paients who have significant respiratory, cardiovascular, gastrointestinal, and cerebral, renal and hepatic disease.
  • Patient who experienced emesis or received antiemetics or steroids within 24 hours.
  • Patients who have history od drug or opioids addiction,
  • Patients who can not communicated,
  • Pregnant woman, morbid obesity

研究者

发起方
Soon Chun Hyang University Hospital Seoul

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