跳至主要内容
临床试验/ISRCTN64888465
ISRCTN64888465进行中(未招募)未知

ow histamine diet and diamino oxidase enzyme supplementation

DR Healthcare España, S.L.0 个研究点目标入组 400 人开始时间: 2022年9月6日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
400

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • •1. Adults over 18 years of age
  • •2. Recent history of two or more symptoms associated with histamine intolerance (headache, dermatological, respiratory, and digestive)
  • •3. Present altered plasma DAO enzyme activity and/or have any of the genetic variants of DAO deficiency:
  • •3.1. SNP-type variants associated with reduced levels of DAO activity (oral mucosal smear or blood)
  • •3.2. rs10156191
  • •3.3. rs1049742
  • •3.4. rs1049793
  • •3.5. rs2052129
  • •4. Not having started dietary treatment (low histamine diet/DAO enzyme supplementation) before starting the study

排除标准

  • •1. Food and/or environmental allergies
  • •2. Have taken pharmacological treatment with antibiotics or probiotic supplements in the last month before the start of the study
  • •3. Being pregnant

研究者

发起方
DR Healthcare España, S.L.

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