ISRCTN64888465进行中(未招募)未知
ow histamine diet and diamino oxidase enzyme supplementation
DR Healthcare España, S.L.0 个研究点目标入组 400 人开始时间: 2022年9月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 400
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adults over 18 years of age
- •2. Recent history of two or more symptoms associated with histamine intolerance (headache, dermatological, respiratory, and digestive)
- •3. Present altered plasma DAO enzyme activity and/or have any of the genetic variants of DAO deficiency:
- •3.1. SNP-type variants associated with reduced levels of DAO activity (oral mucosal smear or blood)
- •3.2. rs10156191
- •3.3. rs1049742
- •3.4. rs1049793
- •3.5. rs2052129
- •4. Not having started dietary treatment (low histamine diet/DAO enzyme supplementation) before starting the study
排除标准
- •1. Food and/or environmental allergies
- •2. Have taken pharmacological treatment with antibiotics or probiotic supplements in the last month before the start of the study
- •3. Being pregnant
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