Point-of-Care C-reactive protein to assist in primary care management of children with lower respiratory tract infectio

Completed

• Conditions: acute bronchitus; cough; Lower Respiratory Tract Infections (LRTI); 10004018; 10024970

• Registration Number: NL-OMON41688
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 354

Inclusion Criteria

- Children aged between 3 months and 12 years presenting to the GP with a non-severe LRTI.
- LRTI will be defined as acute cough (shorter than 21 days) with (reported) fever (>38 °C).
- The parent of the patient should be able to provide written informed consent and be willing to (help to) complete the patient diary.

Exclusion Criteria

- immunodeficiency
- recent (previous four weeks) use of systemic antibiotics and/or corticosteroids
- being severely ill as judged by the GP based on symptoms and signs
- highly suspected of having pneumonia;Being severely ill or highly suspected of pneumonia includes: signs of dehydration, cyanosis, tachypnoe, lower level of consciousness or fever during > 5 days, no food or fluid intake, or otherwise judged as being severely ill by the GP.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome is the % antibiotic prescriptions during 28 days after<br /><br>first consultation. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes include health care use, costs, adverse events, quality of<br /><br>life (QOL), symptoms, and cost-effectiveness.</p><br>