sing Point-of-care C-reactive protein to guide Antibiotic prescribing for Respiratory tract infections in Elderly nursing home residents

Completed

• Conditions: Lower respiratory tract infection; pneumonia; 10024970

• Registration Number: NL-OMON48719
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 671

Inclusion Criteria

Nursing home residents with a new diagnosis *suspected lower respiratory tract
infection*

Exclusion Criteria

- The patient resides at a palliation/hospice care department of the nursing
home
- The patient wishes not to be treated with antibiotics (anymore)
- The patient is already taking antibiotics
- The patient is (also) diagnosed with a different type of infection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>CENTRAL RESEARCH QUESTION:<br /><br>Determinant: use of CRP POCT (yes/no)<br /><br>Outcome: antibiotic prescribing for patients with suspected LRTI at index<br /><br>consultation (yes/no)<br /><br><br /><br>SUB RESEARCH QUESTION 1A:<br /><br>Determinant: signs and symptoms<br /><br>Outcome: CRP-value<br /><br><br /><br>SUB RESEARCH QUESTION 1B:<br /><br>Determinant: CRP-value<br /><br>Outcome: antibiotic prescribing (yes/no)<br /><br><br /><br>SUB RESEARCH QUESTION 2:<br /><br>Determinant: costs related to intervention (CRP POCT and regular health care<br /><br>costs) versus control (regular health care costs)<br /><br>Outcome: percentage of antibiotic prescribing, reduction in antibiotic<br /><br>prescribing in euros.<br /><br><br /><br>SUB RESEARCH QUESTION 3: potential barriers and facilitators for the use and<br /><br>implementation of CRP POCT in NHs.</p><br>