Clinical significance of Malnutrition-Inflammation-Atherosclerosis Syndrome in the patients on maintenance hemodialysis
Not Applicable
Completed
- Conditions
- End-stage renal disease treated with hemodialysis.Urological and Genital DiseasesEnd-stage renal disease
- Registration Number
- ISRCTN61950442
- Lead Sponsor
- Ministry of Science, Education and Sport of the Republic of Croatia
- Brief Summary
2010 results in: https://hrcak.srce.hr/63076 (added 22/05/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 168
Inclusion Criteria
End-stage renal diasese on maintenance hemodialysis lasting at least 3 months.
Exclusion Criteria
1. Previously transplanted
2. Previously treated with peritoneal dialysis
3. History of active infection in the last 3 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Patient survival with or without MIA syndrome at 2 years<br> 2. Survival of patient with MIA syndrome according to randomisation/intervention at 2 years<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Determinantion of independent predictors of mortality in MIA syndrome patients at 2 years<br> 2. Influence of intervention on laboratory parameters of MIA syndrome at 2 years<br> 3. Safety assessement of atorvastatin application, checked after 1, 3, 6, 12 and 24 months according to known precautions for statin use<br> 4. Hospitalisations rate and frequency of patients with or without MIA syndrome at 2 years<br>