Effect of pain killer by different methods after dental treatment

Phase 2

Not yet recruiting

• Conditions: Pulpitis,

• Registration Number: CTRI/2022/05/042412
• Lead Sponsor: Dr Bhumika Rathod

Brief Summary

**Topic**: The efficacy of post endodontic paincontrol using different administration routes for diclofenac sodium in a randomized,double-blind, placebo-controlled study

**Introduction**: Experience of root canal-associatedpain is a major source of fear for patients and a very important concern fordentists. Anxiety, apprehension, fear of dental treatment, and other factorsinfluence patients’ pain perception and reaction thresholds. Management ofendodontic pain is one of the challenging aspects of endodontics.

**Aim and Objective:**The purpose of this clinical trial is to evaluate the analgesic efficacy ofdiclofenac sodium administered through oral and transdermal routes in reducing post-endodonticpain.

**Materials and Methods**:Forty-five patients were randomly allocated into three groups. Group A – diclofenacsodium tablets, Group B – diclofenac sodium (transdermal patch), and Group C –placebo(Vitamin B12). The tablets were given 30 min before the procedure. The visual analogscale (VAS) was used to evaluate the pain score at preoperative and 6, 12, 24, 48h  and 7 days after biomechanicalpreparation.

**Keywords**: Diclofenacsodium; Endodontic treatment; Interappointment pain; Transdermal patch; Oraltablet

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-06-05
• Study Start: 2022-09-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Vital pulp in need of endodontic therapy 2.
• Irreversible pulpitis in molar teeth 3.
• Age – 18–65 years.

Exclusion Criteria

• History of systemic diseases 2.
• History of allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) 3.
• Radiographic evidence of periapical pathosis 4.
• Pregnant or lactating mothers.
• Patient must not have taken any pain killer before 24 hours.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-endodontic pain control will be observed by both routes of administration for diclofenac sodium	6hrs, 12 hrs, 24 hrs

Secondary Outcome Measures

Name	Time	Method
efficacy of oral route of administration of diclofenac sodium compared to transdermal patch for controlling post endodontic pain at different time interval.	6hr, 12hr, 24hr, 48hr and 7 days

Trial Locations

Locations (1)

College of Dental Science and Research Centre; 🇮🇳 Ahmadabad, GUJARAT, India

College of Dental Science and Research Centre

🇮🇳Ahmadabad, GUJARAT, India

Dr Bhumika Rathod

Principal investigator

9727753823

drbhumikapatel2903@gmail.com