Comparative effects of intermittent versus continuous energy restriction on metabolism following matched weight-loss

Completed

• Conditions: Weight-loss; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN13687043
• Lead Sponsor: ighterlife UK Ltd

Brief Summary

1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29508693 (added 24/01/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-08-29
• Study Start: 2016-12-05
• Last Update Posted: 11 February 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

1. Overweight and obese participants (BMI =25 kg/m2)
2. Aged 18 to 65 years
3. Weight-stable (±2 kg) over the preceding three months
4. No significant medical history
5. To control for the potential influence of the menstrual cycle between visits, female participants were either post-menopausal or taking oral contraceptives

Exclusion Criteria

Individuals not meeting the inclusion criteria.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. 6-hour postprandial glucose (glucose, insulin, c-peptide) to a liquid mixed test meal is measured before and after attainment of 5% weight-loss<br> 2. Lipid responses (triacylglycerol, non-esterified fatty acids) to a liquid mixed test meal is measured before and after attainment of 5% weight-loss<br>