Effect of two different anaesthetic drugs (propofol versus desflurane) on higher mental functions undergoing neurosurgery for brsin haemorrhage
- Conditions
- Health Condition 1: null- aSAH Patients with ASA 1,2or3 with Hunt & Hess grade 1,2 or 3 with WFNS grade 1,2 or3
- Registration Number
- CTRI/2015/01/005425
- Lead Sponsor
- PGIMER CHANDIGARH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
(1)Patients scheduled for aSAH surgery with clinical and radiological evidence of cerebral aneurysm.
(2)Age between 18 to 65 yrs.
(3)H and H grade 1 ,2 & 3 and WFNS grade 1, 2 & 3.
(4)ASA 1, ASA 2 and ASA 3 will be included
Exclusion Criteria
(1)Patients with systemic disease other than hypertension and diabetes mellitus.
(2) Patients with infectious diseases and respiratory complications.
(3) Duration of anesthesia more than six hours.
(4) Second operation.
(5) Low level of education.
(6) Patients with known psychiatric disease.
(7) Cardiovascular disease and respiratory impairment.
(8) History of drug abuse.
(9) Known allergy to any of the anesthetic agent to be used in study.
(10)Patients who are unconscious, intubated or tracheostomised even after two weeks following exposure to anesthesia will also be excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method comparision of POCD between study group desflurane and propofol postoperativelyTimepoint: MOCA score 0 to 30
- Secondary Outcome Measures
Name Time Method comparision of haemodynamics and brain bulge between study groups desflurane and propofol intraoperativelyTimepoint: brain bulge score 0 to4