Comparative effect of propofol versus sevoflurane on renal ischemia/reperfusion injury after elective open abdominal aortic aneurysm repair. A random

Not Applicable

• Conditions: Circulatory System; Surgery; renal ischemia/reperfusion injury; Anaesthesia

• Registration Number: PACTR201505001095139
• Lead Sponsor: Minoufiya University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-04-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

50 ASA class II or III patients scheduled for elective infra-renal AAA repair.

Exclusion Criteria

Patients were excluded from the study if they needed concomitant procedures other than AAA repair, had experienced an acute coronary syndrome within 3 months, or were >85 years of age.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rinary specific kidney proteins (N-acetyl-beta-Dglucosamidase, alpha-1-microglobulin, glutathione transferase-pi, glutathione transferase-alpha);creatinine clearance and serum cystatin

Secondary Outcome Measures

Name	Time	Method
Serum pro-inflammatory cytokines (tumor necrosis factor-¿ and interleukin 1-¿)