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临床试验/CTRI/2026/04/109215
CTRI/2026/04/109215尚未招募不适用

Artificial Intelligence and Its clinical Relevance in Gastrointestinal Malignancies: A Comprehensive Study on Rectal, Pancreatic, and Liver Cancer imaging Data.

Dr. Reena Engineer1 个研究点 分布在 1 个国家目标入组 750 人开始时间: 2026年9月16日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
750
试验地点
1

研究概览

简要总结

This study uses artificial intelligence (AI) to improve the treatment of rectal, pancreatic, and liver cancers. By analyzing medical images like CT scans, MRIs, PET scansanddigitis****ed pathologyslide****s AI can help doctors understand how tumors are responding to treatment and predict future outcomes. This approach aims to make cancer treatment more personalized, allowing doctors to choose the most effective treatment plan for each patient.

Currently, predicting how well a patient will respond to cancer treatments is difficult, as there are no reliable tests for this. This study will create AI tools that can predict which patients will respond well to treatment, which might need a different approach, and how long they are likely to survive or stay cancer-free. The study will analyze medical images from all TMC hospital to develop these tools and improve decision-making in cancer care.

We (TMH) will be providing imaging data of pancreatic , hepatic and rectal malignancies to Dr Satish Viswanath Associate Professor, Emory University, Atlanta,. Emory University will run specialised software for radiomic feature extraction . We will use these radiomic feature for clinical correlation .

The main goal of this study is to use AI to provide more accurate predictions and help doctors make better treatment decisions. By training AI to predict treatment responses, survival chances, and the effectiveness of different therapies, the researchers hope to improve cancer outcomes. This personalized approach could lead to better survival rates, fewer unnecessary treatments, and an overall improvement in the quality of care for cancer patients.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • Patients aged 18 years and older.
  • Patients registered at Tata Memorial Hospital as outpatients between 2015 and
  • Confirmed diagnosis of rectal carcinoma.
  • Confirmed diagnosis of pancreatic carcinoma classified as borderline resectable (BRPC) or locally advanced (LAPC).
  • Confirmed diagnosis of hepatocellular carcinoma (liver cancer).
  • Patients who have undergone neoadjuvant chemoradiotherapy for rectal cancer.
  • Patients who have received stereotactic body radiation therapy (SBRT) for pancreatic cancer.
  • Patients who have received SBRT and systemic therapy for liver cancer.
  • Availability of baseline imaging data (CT or MRI) and digitized pathology slides on the Picture Archiving and Communication System (PACS) in DICOM format.

排除标准

  • Non availability of online DICOM images.
  • Non availability of clinical data.

研究者

发起方
Dr. Reena Engineer
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

REENA ENGINEER

TATA MEMORIAL HOSPITAL, MUMBAI

研究点 (1)

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