Do High Doses of Protein Supplements Affect Serum Lipid Profiles?

Completed

• Conditions: To Study the Effects of Protein Supplements on Blood Tests
• Interventions: Dietary Supplement: protein supplement

• Registration Number: NCT04170036
• Lead Sponsor: Near East University, Turkey

Brief Summary

Protein supplements are widely used among people going to the gym. The effects of these substances on blood biochemical, hematological, inflammatuary, glucose metabolism markers and lipid profile is not well known. The previous studies on this issue give inconclusive results. So the investigators aimed to investigate this subject and compare the blood tests between subjects using and not using protein supplements.

Detailed Description

As more people are doing regular exercises, people using protein supplements are also increasing. The effects of these substances on blood lipid profiles, biochemical, hematological parameters, inflammatory and glucose metabolism markers are not well known. So the investigators of this study planned to search the effects of these substances on blood tests. Totally 69 subjects going to the gym for at least three preceding months were included to the study. They were divided into two groups: the ones using protein supplements and the ones who never used these substances. Demographic and clinical characteristics were recorded. Dietician assessed the dietary habits of the subjects. Blood was drawn for the tests mentioned above from all of the subjects. And the results were compared between the two groups.

Study Timeline

• Study Start: 2019-03-15
• Primary Completion: 2019-08-15
• Study Completion: 2019-08-20
• Status Verified: 2019-11
• Study First Submitted: 2019-11-15
• Study First Submitted QC: 2019-11-17
• Last Update Submitted: 2019-11-19
• Study First Posted: 2019-11-20
• Last Update Posted: 2019-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 69

Inclusion Criteria

• Going to the gym for at least three preceding months

Exclusion Criteria

• Any kind of acute or chronic illness
• Abnormality on electrocardiography
• Body-mass index>30 kg/m2
• Use of any kind of drugs
• Hypertension at the time of recruitment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Protein supplement group	protein supplement	The group of subjects who use protein supplements at least for the preceding three months

Primary Outcome Measures

Name	Time	Method
Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)	1 day	No unit
Serum hemoglobine level	1 day	g/dl
Serum glucose level	1 day	mg/dl
Serum insulin level	1 day	uU/ml
Serum mean platelet volume	1 day	fL
Serum platelet level	1 day	x10\^3/uL
Serum uric acid level	1 day	mg/dl
Serum calcium level	1 day	mg/dl
Serum high-density lipoprotein level	1 day	mg/dl
Serum C-reactive protein level	1 day	mg/dl
Serum potassium level	1 day	mmol/L
Serum total cholesterol level	1 day	mg/dl
Serum sodium level	1 day	mmol/L
Serum creatinine level	1 day	mg/dl
Serum urea level	1 day	mg/dl
Serum gama-glutamile transferase level	1 day	U/L
Serum aspartate aminotransferase level	1 day	U/L
Serum alanine aminotransferase level	1 day	U/L
Serum magnesium level	1 day	mg/dl
Serum low-density lipoprotein level	1 day	mg/dl
Serum triglyceride level	1 day	mg/dl

Trial Locations

Locations (1)

Near East University; 🇨🇾 Nicosia, Cyprus