Ridge Splitting With Simultaneous Implant Placement Using i-PRF With Guided Bone Regeneration: a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Measurements of the amount of bone formation in millimeters around immediately placed dental implants
研究概览
简要总结
Sohn introduced the concept of sticky bone in which i-PRF is mixed with the granules of bone graft, leading to fabrication of growth factors-enriched bone graft matrix using autologous fibrin glue. This minimizes bone loss and accelerates tissue healing during healing period. The present study was conducted to evaluate the clinical and radiographic outcomes following the application of the alveolar ridge splitting in combination with the use of guided bone regeneration (GBR) with or without i-PRF (sticky bone), associated with immediate implant placement in patients with horizontally atrophic jaw bones.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •good general health at the time of surgery.
- •at least 3 months of healing after tooth extraction.
- •horizontally compromised alveolar ridges at least 10 mm high and 3 mm wide.
排除标准
- •a vertical bone defect in the edentulous ridge.
- •thick cortex in the labial/buccal with less cancellous bone inside
- •obvious undercut on the labial/buccal side.
- •uncontrolled periodontal conditions or other oral disorders.
- •history of radiotherapy in the head and neck region.
- •uncontrolled diabetes mellitus or other systematic disorders.
- •Pregnancy.
- •non-compliant patients.
- •allergic reaction to the medications used
结局指标
主要结局
Measurements of the amount of bone formation in millimeters around immediately placed dental implants
时间窗: 9 months
Measurements of the amount of bone formation in millimeters using GBR with or without the combined effect of i-PRF in the ridge splitting following immediate implant placement.
次要结局
未报告次要终点
研究者
Dalia Rasheed Issa
principal investigator
Kafrelsheikh University