Attention Training for Learning Enhancement and Resilience Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Posit Science Corporation
- Enrollment
- 83
- Locations
- 2
- Primary Endpoint
- Attention Measures aimed to test attention
Study Overview
Brief Summary
Healthy aging is associated with a decline in multiple cognitive domains, as well as motor control function. The long-term consequences of cognitive and functional impairment resulting from age-related cognitive decline are well documented in the scientific and clinical literature, with significant evidence of related problems with independent functional abilities. This study aims to understand how the experimental computer program can affect cognition and attention in participants with age-related cognitive decline.
Detailed Description
Following consent, participants will engage in an assessment process to determine eligibility. Once eligibility is confirmed, participants will be scheduled for another assessment session to determine current level of cognitive function. This process consists of paper-pencil surveys and computerized tests. Following the assessment process, participants will engage in an Internet browser-delivered training sessions conducted on any internet-accessible computer. The computerized training sessions can be done up to 7 times a week (once a day) or at the participant's convenience (the recommended time commitment is 5 times a week). Following the completion of training, the participant's cognitive function will be re-assessed. Participation is voluntary and participants may withdraw from the study at any time.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 65 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Participants must be 65 years of age or older
- •Participants must have a diagnosis of age-related cognitive decline as confirmed by interview and performance on screening assessments
- •Participants must be fluent English speakers
- •Participants must have adequate visual, auditory, and motor capacity to use computerized intervention
Exclusion Criteria
- •Participants with diagnosis of PTSD, depression or other psychologically diagnosable emotional disorder
- •Participants with a history of conditions that could affect thinking abilities, including brain injury, mental illness, cancer, or other neurological conditions (multiple sclerosis, seizure disorder), HIV/AIDS will be excluded
- •Participants enrolled in another concurrent research study will be excluded
- •Participants who have difficulty performing assessments or comprehending or following spoken instructions, in the judgment of the screening clinician, will be excluded
- •Participants with a current or significant past history of substance abuse will be excluded
- •Participants who show signs of suicidal ideations or behaviors will be excluded and referred for appropriate treatment
Arms & Interventions
Experimental Treatment
Computerized plasticity-based adaptive cognitive training requiring a total maximum of 36 treatment sessions, 4-5 times weekly, one hour each session.
Intervention: Computerized Plasticity-Based Adaptive Cognitive Training (Other)
Active Comparator
Commercially available computerized training requiring a total maximum of 36 treatment sessions, 4-5 times weekly, one hour each session.
Intervention: Commercially available computerized training (Other)
Outcomes
Primary Outcomes
Attention Measures aimed to test attention
Time Frame: 6 months
Measures aimed to test attention
Functional Capacity
Time Frame: 6 month
Performance on directly observable functional measure
Executive Function
Time Frame: 6 months
Tasks targeting inhibitory control
Secondary Outcomes
- Quality of Sleep(6 months)