Is Oral or Intravenous administration of antibiotics superior in the treatment of moderate cellulitis?

Not Applicable

• Conditions: Cellulitis; Infection - Other infectious diseases; Skin - Other skin conditions

• Registration Number: ACTRN12618001840279
• Lead Sponsor: Ashley Loughman

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-12
• Last Update Posted: 19 November 2018

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 412

Inclusion Criteria

Presence of Cellulitis as defined by the presence of acute dermal/epidermal inflammation lasting <5 days and of probable infective aetiology. At least one marker of moderate severity, either a marker of systemic inflammatory response (documented temperature >37.8c, tachycardia >90bpm, systemic symptoms inc. malaise, flu like symptoms, nausea and vomiting or elevated inflammatory markers) or a risk factor eg. Diabetes, homelessness, etc.

Exclusion Criteria

Patients will be excluded if they are unable to or decline consent; have mild cellulitis suitable for immediate discharge(limited area <10cm in longest axis, no risk factors, no systemic symptoms); cellulitis complicating trauma, intravenous drug use or recent (<30 days) surgical sites; periorbital cellulitis; immunosuppressed patients; morbidly obese patients; a diagnosis other than cellulitis or complicated cellulitis (severe sepsis, extensive bullous changes, abscess formation or suspected necrotising deep tissue involvement); vomiting precluding oral therapy or prior treatment with per protocol oral antimicrobials for >48 hours or parenteral antimicrobials

Study & Design

• Study Type: Interventional
• Study Design: Not specified