Randomized controlled trial to evaluate the prediction of the immunotherapy response based on HLA-type.
Not Applicable
- Conditions
- Gastric and colorectal cancer
- Registration Number
- JPRN-UMIN000037483
- Lead Sponsor
- The Japanese Society of Strategies for Cancer Research and Therapy
- Brief Summary
Our results showed that it is beneficial to examine HLA antigens preoperatively. We observed long term survivors who were given effective therapy, whereas those who died shortly after gastrectomy were given ineffective therapy. We, however, failed to find a specific HLA profile to treatment response.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 542
Inclusion Criteria
Not provided
Exclusion Criteria
1. Double cancer. 2. Mucosal and no lymph node metastasis. 3. Prior cytotoxic or radiation therapy. 4. Abnormal bone marrow, hepatic and renal function 5. Severe cardiac, hepatic and lung failure, and an attending doctor was considered unsuitable.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method