Can Neurally Adjusted Ventilatory Assist improve the outcome of mechanical ventilation compared to Pressure Support Ventilation? A multicenter randomized clinical trial.

Not Applicable

• Conditions: Duration of mechanical ventilation during acute respiratory failure; Respiratory - Other respiratory disorders / diseases; Lenght of stay in intensive care unit in patient with acute respiratory failure

• Registration Number: ACTRN12612000815864
• Lead Sponsor: Dipartimento di Medicina Traslazionale, Universita del Piemonte Orientale Amedeo Avogadro, Alessandria-Novara-Vercelli, Italy.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Intubated patients
Previous mechanical ventilation >= 24 hours
Ability to effectively trigger the ventilator
Expected ventilatory assistance >= 48 hours
No scheduled surgery
No inclusion in other research protocol
No neuromuscular or neurologic disease
Absence of contraindications to feeding tube positioning (including esophageal surgery in the previous 12 months and/or history of esophageal varices)
PaO2/FiO2 >150 with PEEP >= 5 cmH2O

Exclusion Criteria

Lack of informed consent or refusal
Organ failure >= 3
Poor short term prognosis or decision to limit life support

Study & Design

• Study Type: Interventional
• Study Design: Not specified