Analysis of ventilatory dynamics under two different positive end-expiratory pressure: a 4D-CT study
- Conditions
- acute respiratory distress syndrome
- Registration Number
- JPRN-UMIN000049583
- Lead Sponsor
- Jichi Medical University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 40
Not provided
- If pneumothorax or mediastinal emphysema is present - If the patient has severe emphysema - If the physician determines that the patient is at high risk of lung injury due to positive pressure - Patients with severe asthma or acute exacerbations of COPD - unstable hemodynamics or expected to be unstable hemodynamics (if stable under catecholamine administration, omit from the exclusion criteria) - Significantly elevated cerebral pressure, if the physician determines that high PEEP should be avoided - If a pacemaker or implantable cardioverter defibrillator is placed in the body - Pregnant women - Patient and family members are unable to give consent - Other cases in which the physician deems it inappropriate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main objectives of this study are to evaluate the following points in the lung areas among the different PEEP groups 1. the proportion and distribution of tidal recruitment in the alveoli 2. the proportion and distribution of over-inflation of the alveoli 3. proportion and distribution of alveolar inflation rate and movement
- Secondary Outcome Measures
Name Time Method