Short term effects of low caffeine energy drinks on blood vessel and heart functions in healthy volunteers

Not Applicable

Completed

• Conditions: Determining the effect of energy drink consumption on heart and blood vessel function in healthy volunteers; Circulatory System

• Registration Number: ISRCTN40313372
• Lead Sponsor: Ankara University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-01-01
• Study Start: 2021-10-19
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Healthy volunteers giving informed consent

Exclusion Criteria

1. Any abnormalities in their baseline screening echocardiographic examination
2. Heavy caffeine consumers (>200 mg/day)
3. Smoke >5 cigarettes/day
4. Low BMI (<18.5 kg/m²) or obese individuals (BMI>30 kg/m²)
5. Acute infection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The change in endothelial flow mediated dilation (FMD) is measured before and 60 minutes after energy drink consumption.

Secondary Outcome Measures

Name	Time	Method
The change in myocardial strain levels is measured using Echocardiographic images for 2 dimensional speckle tracking echocardiography of left and right ventricles recorded before and 60 minutes after study drink consumption, which are then analyzed offline by an investigator blind to patient data.