Patterns Of Left Ventricular Remodeling In Patients With Aortic Stenosis Assessed By Two-Dimensional And Three-Dimensional Echocardiography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic Stenosis
- Sponsor
- Lahey Clinic
- Locations
- 1
- Primary Endpoint
- Evaluate 2-dimensional and 3-dimensional echocardiography for LV patterns of remodeling and hypertrophy
- Status
- Withdrawn
- Last Updated
- 14 years ago
Overview
Brief Summary
This preliminary study will compare the effectiveness of two-dimensional and three-dimensional echocardiographic measurements of wall thickness and left ventricular mass in patients with Aortic Stenosis
Detailed Description
This study will evaluate left ventricular patterns of remodeling and hypertrophy in patients with aortic stenosis, and compare two-dimensional echocardiography measurements (wall thickness) with three-dimensional echocardiography data(left ventricular mass). Along with a second objective to assess Doppler diastolic filling indices associated with the various patterns of left ventricular remodeling. Previous studies(see reference list) were primarily derived from two-dimensional echo data set(based on wall thickness). Various patterns of left ventricular remodeling have been described in response to increased pressure overload. Three-dimensional echocardiography is a relatively new technique that is being increasingly used in the Echocardiography Lab in selected patients. This technique holds promise of being more accurate for volume-related measurements than the standard 2-dimensional echocardiography techniques.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Subjects more than 18 yrs of age through 90 yrs of age
- •Both male and female
- •Patients with moderate or severe isolated Aortic Stenosis
- •Patients who have been referred for both two-dimensional and three- dimensional echocardiographies.
Exclusion Criteria
- •Poor acoustic windows
- •h/o CAD and wall motion abnormality
Outcomes
Primary Outcomes
Evaluate 2-dimensional and 3-dimensional echocardiography for LV patterns of remodeling and hypertrophy
Time Frame: 1 hour
Secondary Outcomes
- Assess doppler diastolic filling indices for patterns of LV remodeling(1 hour)