The Effects of Dairy Products on Energy Balance

Not Applicable

Completed

• Conditions: Obesity
• Interventions: Other: High Calcium intake from dairy products

• Registration Number: NCT01199835
• Lead Sponsor: University of Copenhagen

Brief Summary

The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately overweight men and women over 24 weeks.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2010-09-08
• Study First Submitted QC: 2010-09-10
• Study First Posted: 2010-09-13
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Status Verified: 2014-06
• Last Update Submitted: 2014-06-10
• Last Update Posted: 2014-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• men and women,
• medium overweight (body mass index 28-36 kg/m2),
• 18-60 years old,
• low habitual calcium intake (<800 mg/d)

Exclusion Criteria

• milk allergy, infection diseases and diabetes,
• intake of dietary supplements,
• smoking,
• pregnancy and/or breast feeding,
• any medications known to affect the outcome measurements,
• weigh reducing diet,
• gastrointestinal diseases,
• participation in other intervention studies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
high calcium	High Calcium intake from dairy products	Dietary intake of calcium \~ 1500 mg/ d, including \~1200 mg/d from dairy products
Low calcium	High Calcium intake from dairy products	Low dietary intake of calcium, i.e. \~ \<600 mg/d, including 0-1 portion of dairy products

Primary Outcome Measures

Name	Time	Method
Fecal fat excretion	24 weeks
Body weight	24 weeks
body composition	24 weeks

Secondary Outcome Measures

Name	Time	Method
Resting energy expenditure	24 weeks
Blood pressure	24 weeks
Appetite regulation	24 weeks
Lipid profile	24 weeks
Intestinal micro flora	24 weeks
Metabolomics in urine, feces and blood	24 week
calcium excretion	24 weeks
bone markers	24 weeks
vitamin D status	24 weeks
calcium status	24 weeks
lipid metabolism	24 weeks

Trial Locations

Locations (1)

Department of Exercise, Nutrition and Sports, Faculty of Sciences, University of Copenhagen; 🇩🇰 Frederiksberg, Denmark