NCT02327117已完成不适用
Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Hb Level 48 Hours After Total Knee Arthroplasty
研究概览
简要总结
Total Knee Arthroplasty (TKA) is a common orthopedic surgery usually leads to Bleeding. The null hypothesis of this study was that TA has no effect on post surgical bleeding in patients undergoes TKA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals with osteoarthritis who indicated for primary TKA.
排除标准
- •Previous history of ceberovascular diseases
- •Previous history of myocardial infarction
- •Candidates for bilateral TKA
研究组 & 干预措施
Tranexamic acid
Experimental
干预措施: Tranexamic Acid (Drug)
Normal Saline
Placebo Comparator
干预措施: Normal saline (Drug)
结局指标
主要结局
Hb Level 48 Hours After Total Knee Arthroplasty
时间窗: 48 hours after TKA
次要结局
未报告次要终点
研究者
Amin Nemati
Orthopedic surgery resident,Orthopedic department,Alzahra hospital,Isfahan University of Medical Sciences,Isfahan,Iran
Isfahan University of Medical Sciences
研究点 (1)
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