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Nasal Mask and Prong Use in Non-invasive Ventilation for Newborns

Not Applicable
Conditions
Bronchopulmonary Dysplasia
Interventions
Device: binasal prongs
Device: nasal mask
Registration Number
NCT01989442
Lead Sponsor
Ankara University
Brief Summary

The study aims to investigate efficacy and safety of nasal mask and prongs used in non-invasive ventilation in newborns by using esophageal pressure transducer.

The parameters including ventilation duration, hospitalization duration, pulmonary outcomes and side effects will be evaluated.

Detailed Description

Although it seems as more non-invasive there is still lack of data especially on efficacy of nasal mask use in NIV for newborns. By using esophageal pressure transducers we will evaluate the pressure supplied by the ventilation mode and compare it with more commonly used nasal prongs. The investigators will test the hypothesis of equivalence of nasal mask in comparison to prongs with better safety parameters.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • all newborns who require NIV as first line treatment as respiratory support in delivery room or neonatal intensive care unit
Exclusion Criteria
  • who are intubated in delivery room or neonatal intensive care unit before randomization
  • with congenital anomaly
  • patients who require NIV more than 3 days

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
nasal prongbinasal prongspatients who receive NIV by nasal prongs as interface after randomization
Nasal Masknasal maskpatients who receive NIV by nasal mask interface after randomization
Primary Outcome Measures
NameTimeMethod
failure of NIV1 year

patients who require endotracheal intubation after NIV treatment

Secondary Outcome Measures
NameTimeMethod
ventilation duration3 days

both NIV and mechanical ventilation durations will be evaluated

Trial Locations

Locations (1)

Ankara University

🇹🇷

Ankara, Turkey

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