Effect of Positive End Expiratory Pressure (PEEP) on Cerebral Oxymetry During Laparoscopy
Not Applicable
Completed
- Conditions
- Cerebral Ischemia
- Interventions
- Procedure: positive end expiratory pressureProcedure: zero end-expiratory pressure
- Registration Number
- NCT01436812
- Lead Sponsor
- Gachon University Gil Medical Center
- Brief Summary
The investigators hypothesized that positive end expiratory pressure (PEEP) would increase the regional oxygen saturation (rSO2).
- Detailed Description
The investigators hypothesized that PEEP would increase the rSO2 during laparoscopic surgery by improving oxygenation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- ASA PS I or II adult patient undergoing laparoscopic low anterior resection with Trendelenburg position
Exclusion Criteria
- Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index > 30) were excluded from this study.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description zero end-expiratory pressure positive end expiratory pressure not applying PEEP during operation just applying TV=IBW\*6-8ml IBW = (male; 50+0.91\[(Ht-cm)-152.4\], female; 45.5 +0.91\[(Ht-cm)-152.4\], RR 8-12/min, positive end expiratory pressure zero end-expiratory pressure applying PEEP 10cmH2O during operation just applying TV=IBW\*6-8ml IBW = (male; 50+0.91\[(Ht-cm)-152.4\], female; 45.5 +0.91\[(Ht-cm)-152.4\], RR 8-12/min,
- Primary Outcome Measures
Name Time Method cerebral ischemia change from baseline in rSO2 at every events induction 10 min, Pneumoperitoneum 20 min, after PEEP apply 40 min, time of operation ending cerebral oxymetry, cerebral perfusion pressure record
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Gachon University Gil Hospital
🇰🇷Incheon, Korea, Republic of