NL-OMON47173已完成不适用
The role of glutamate in cognition in adults with chromosome 22q11 deletion syndrome - Glutamate and cognition in adults with 22q11DS
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •For participants with 22q11DS:
- •Confirmed diagnosis of 22q11DS established by FISH, microarray or MLPA analysis.
- •Age 18 and older and mentally competent to give informed consent.
- •No psychopharmacological treatment at the time of inclusion .
- •No presence of a physical/medical condition that may interfere with the study.
- •No contraindication for MRI;For healthy controls:
- •Healthy subjects will be matched for age, gender and ethnicity.
- •No use of any psychopharmacological treatment at the time of inclusion.
- •No presence of a physical/medical condition that may interfere with the study.
- •No contraindication for MRI
排除标准
- •For participants with 22q11DS:
- •Other chromosomal abnormalities
- •Current substance abuse / dependence
- •Comorbid psychiatric / neurologic disorder
- •Contraindications for Riluzole;For healthy controls:
- •Any chromosomal abnormalities
- •Current substance abuse / dependence
- •A psychiatric or neurologic disorder
- •Contraindications for riluzole
研究者
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