NL-OMON52428招募中不适用
The role of glutamate and GABA in cognition in subjects with chromosome 22q11.2 copy number variants - Glutamate, GABA and cognition in subjects with 22q11.2 CNVs
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 80 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16 至 99（—）
入选标准
- •For participants with 22q11.2 CNVs:
- •Confirmed diagnosis of 22q11.2 CNVs established by FISH, microarray or MLPA
- •Age 16 and older and mentally competent to give informed consent.
- •No presence of a physical/medical condition that may interfere with the
- •No contraindication for MRI.
- •For healthy controls:
- •Healthy subjects will be matched for age and gender.
- •No presence of a physical/medical condition that may interfere with the
- •No contraindication for MRI
排除标准
- •For participants with 22q11.2CNVs:
- •Other chromosomal abnormalities
- •Current substance abuse / dependence
- •Comorbid psychiatric / neurological disorder
- •Pregnancy
- •For the optional dopamine transporter study, subjects are excluded that
- •participated in a research project in which they received a radiation burden in
- •the past year, and when they use medication that occupies the dopamine
- •transporter.
- •For healthy controls:
- •Any chromosomal abnormalities
- •Current substance abuse / dependence
- •A psychiatric or neurologic disorder
- •Pregnancy
- •For the optional dopamine transporter study, subjects are excluded that
- •participated in a research project in which they received a radiation burden in
- •the past year, and when they use medication that occupies the dopamine
- •transporter
研究者
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